Multiple Ohio River access points less than 20 miles from confluence with Mississippi River
Interstate 57 runs centrally though the county providing easy access to Interstate 24 to the north and Interstate 55 to the south
Class 1 railway access via Canadian National, including existing spur to Ohio River offloading at Mound City
Other incentives: Empowerment Zone, Enterprise Zone (in Mounds and Mound City), TIF District (in Ullin and Mounds)