Interstate Highway 24 runs through the center of the county, providing direct access to Paducah, Nashville, St. Louis, and Chicago.
Massac County is served by the Paducah &Illinois Railroad, jointly owned by Canadian National Railway, BNSF Railway, and the Paducah & Louisville Railway, crossing the Ohio River on the Metropolis Bridge.
Multiple Ohio River access points including boat ramps and possible barge offloading sites
Electric Energy Inc. power plant site in Joppa to be converted into Joppa Battery Energy Storage system with minimum storage capacity of 37 MW.
Other incentives: Other incentives: Enterprise Zone, TIF District (in Metropolis), Illinois Energy Transition Community Support grants, Partnerships for Opportunity and Workforce and Economic Revitalization (POWER) Initiative